The nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human BST-2/Tetherin

S Giese, SP Lawrence, M Mazzon, BM Nijmeijer… - Viruses, 2020 - mdpi.com
… , HIV-2 does not express Vpu but has adapted its envelope (Env) … 2693BA and the HIV-2
strain 7312 showed smaller effects (… Human immunodeficiency virus type 1 (HIV-1) AD8-infected …

[HTML][HTML] Toward a macaque model of HIV-1 infection: Roadblocks, progress, and future strategies

R Thippeshappa, JT Kimata, D Kaushal - Frontiers in Microbiology, 2020 - frontiersin.org
line resulted in an in vitro adapted HIV-1 derivative (NL-DT5R), which replicated well in the
CM T-cell line (… region of simian immunodeficiency virus SIVgsn166 vpu. The resultant clone, …

HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2

B Olety, P Peters, Y Wu, Y Usami, H Göttlinger - Science Advances, 2021 - science.org
… In contrast to HIV-1, most simian immunodeficiency virusesVpu without altering the vpu
initiation codon did not affect Env … T cell line is exceptionally susceptible to infection with cell-free …

[HTML][HTML] Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5

AO Angerstein, CA Stoneham, PW Ramirez… - Virology, 2020 - Elsevier
… usually found in laboratory-adapted strains that are easily … sensitive to SERINC5 (LAI and
SF162) and three of which we … Human immunodeficiency virus type 1 env clones from acute …

[HTML][HTML] Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses

SBH Gumbs, R Kübler, L Gharu, PJ Schipper… - Journal of …, 2022 - Springer
… , the main viral CNS reservoir, is imperative. Here, we provide a comprehensive comparison
of human microglial culture models: cultured primary microglia (pMG), microglial cell lines, …

Genetically Modified Immune Cells Secreting Broadly Neutralizing Antibodies against HIV: Restoration of Systemic Immunity

A Powell - 2021 - search.proquest.com
… regression to acquired immunodeficiency syndrome (AIDS), … -specific CD8+ T cell response,
CD4+ T cell function, and the … epitope escape, as well as adapt to future research on more …